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L-arginine in combination with other medications was well-tolerated, safe, and effective for mild-to-moderate ED. A randomized, double-blind, crossover, placebo-controlled comparative clinical trial of arginine aspartate plus adenosine monophosphate for the intermittent treatment of male erectile dysfunction [Abstract]. Erectile dysfunction (ED), also called impotence, is the inability to have or maintain an erection.

Despite the known health benefits of folate, researchers say caution is needed in regard to folate supplements. Treatment of erectile dysfunction with pycnogenol and L-arginine [Abstract]. This supplement is extracted from the bark of the African yohimbe tree. Both men are given between 9 and 15 months to live. Thirty-one percent of men with ED taking 5 grams of L-arginine per day experienced significant improvements in sexual function.

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